Cardinals at Buccaneers odds, picks and predictions

Game Overview

The Arizona Cardinals (3-8) travel to face the Tampa Bay Buccaneers (6-5) on Sunday for Week 13 NFL action. The kickoff is set at Raymond James Stadium in Tampa, Florida. Both teams aim to strengthen their footing as the regular season begins to tighten.

Betting Odds

According to the latest odds from Tipico Sportsbook, Tampa Bay enters as the favorite. The Buccaneers are listed at -6.5 points, with an over/under set around 41.5 total points. These numbers reflect the betting market’s expectation of a moderately low-scoring game and Tampa Bay maintaining its home-field advantage.

Recent Team Performance

Cardinals: Arizona comes into this game after a rough season, struggling to find consistency on both offense and defense. Quarterback Kyler Murray’s return has brought some life back to the offense, but the team still faces defensive concerns and turnover issues.
Buccaneers: Tampa Bay, led by Baker Mayfield, has shown improved offensive rhythm over recent weeks. Their defense has remained solid, particularly against the run, and they’ve performed better at home than on the road.

Key Matchups

Baker Mayfield vs. Cardinals Secondary: The Cardinals’ defense has been vulnerable against efficient passing, making Mayfield’s connection with Mike Evans a crucial factor.
Kyler Murray’s Mobility: Tampa Bay’s aggressive front seven could pressure Murray, but his scrambling ability may open up opportunities on broken plays.
Turnover Margin: Both teams have struggled at times with ball security, making takeaways a potential game-changer.

Expert Prediction

Tampa Bay’s mix of defensive strength and offensive balance gives it the upper hand at home. The Cardinals’ offense can keep them in the contest briefly, but the Buccaneers’ ability to control the tempo should lead to a late separation on the scoreboard.

Prediction: Buccaneers 27, Cardinals 17
Pick Against the Spread (ATS): Buccaneers -6.5
Over/Under: Lean toward the Under (41.5)

Betting Insight

The under has hit in four of Tampa Bay’s last five home games, while Arizona has covered the spread only once in its past five road appearances. These trends suggest a controlled game tempo and limited scoring bursts from either side.

Author’s Summary: Tampa Bay’s defense and home-field advantage position the Buccaneers to cover the spread, while Arizona’s inconsistency limits its upset potential.

Sportsbook Wire — 2025-11-29