Developing new topical drugs or cosmetics requires a long, expensive research and marketing process, with each launch estimated to cost about $3 billion.
With a growing demand to replace animal testing, skin-on-chip platforms could be a promising, ethical replacement.
“It is timely and necessary to provide an overview of the state-of-the-art microphysiological systems targeting human skin models for in vitro testing of pharmaceutical or cosmetic compounds, as well as wound healing models, to outline future directions based on the present research achievements,”
said author Ciprian Iliescu. The skin-on-chip platforms review by Ghiță-Răileanu shows promising results and challenges in replacing animal models.
Author's summary: Skin-on-chip is a promising alternative to animal testing.