A major trial in the UK is investigating a panel of blood tests to detect dementia more quickly and accurately across diverse populations. This landmark study is led by the University of Bristol and North Bristol NHS Trust.
The trial forms part of the broader Blood Biomarker Challenge, funded by leading dementia charities and the People’s Postcode Lottery. By including participants from minority ethnic groups, older age ranges, and individuals with other health conditions, the study aims to show how blood-based diagnostics could revolutionize dementia care within the NHS.
The READ-OUT (REAl World Dementia OUTcomes) research team at Dementias Platform UK (DPUK) is leading the initiative. Their goal is to address existing gaps in dementia diagnosis, improve early detection, and enhance outcomes for people living with dementia.
Elizabeth Coulthard, Professor of Cognitive Neurology at the University of Bristol and Consultant Neurologist at North Bristol NHS Trust, stated: “We’re in an incredibly exciting time for dementia research right now, with new drugs that can slow early Alzheimer’s disease. Although these are not yet approved for use in the NHS, we urgently need to revolutionise the way we diagnose people in this country."
This trial represents a significant step toward more accessible and accurate dementia diagnosis, potentially transforming care for patients throughout the UK.
Author’s summary: This UK trial explores blood-based tests to enable earlier and more accurate dementia diagnosis, aiming to transform detection and care for diverse populations in real-world NHS settings.