Timberwolves vs. Knicks Prediction, Odds and Best NBA Prop Bets for Wednesday, Nov. 5

Timberwolves vs. Knicks Prediction, Odds and Best NBA Prop Bets for Wednesday, Nov. 5

Two franchises that have been closely linked since a major trade before the 2024–25 season will meet again for the first time in the 2025–26 campaign on Wednesday. The New York Knicks and Karl-Anthony Towns will host the Minnesota Timberwolves and Julius Randle, who recently secured a win over the Brooklyn Nets on Monday night.

Minnesota continues to manage without Anthony Edwards due to a hamstring issue, yet the team has strung together two consecutive victories and is aiming to make another deep playoff run, potentially a third straight Western Conference Finals appearance. Edwards has now been upgraded to questionable for Wednesday’s matchup, giving the Wolves a possible boost.

The Knicks, semifinalists in the Eastern Conference last season, have started this year 4–3, fueled by a dominant four-game home winning streak. They recently defeated Chicago and Washington in consecutive games over Sunday and Monday, setting themselves up as home favorites going into Wednesday’s contest.

With several players crossing paths due to last year’s blockbuster trade, both rosters feature familiar faces, adding extra intrigue to what promises to be a competitive and story-filled night at Madison Square Garden.

Odds via DraftKings Sportsbook.

Author Summary

The Knicks and Timberwolves face off in a high-stakes early-season clash highlighting familiar stars, recent momentum, and the lingering impact of their major 2024 trade.

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Sports Illustrated Sports Illustrated — 2025-11-05

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